Survival-associated eQTLs across different cancer types
We identified 22,212 eQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
|
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
|---|---|---|---|---|---|---|---|---|---|
| THCA | rs45452391 | chr1:220789525 | G/A | 2.55E-5 | 488 | 15.9 | 17.1 | 0.23 | KM Plot |
| THCA | rs45476291 | chr14:59836655 | A/G | 0.000151 | 488 | 16.25 | 14.9 | 5.45 | KM Plot |
| THCA | rs45478094 | chr6:24418878 | G/A | 5.33E-15 | 489 | 16.33 | 14.85 | 11.07 | KM Plot |
| THCA | rs45479292 | chr19:43570853 | T/C | 0.000246 | 486 | 15.32 | 18.93 | 10.08 | KM Plot |
| THCA | rs45482500 | chr6:24419081 | C/T | 6.22E-15 | 488 | 16.3 | 14.85 | 11.07 | KM Plot |
| THCA | rs4548873 | chr16:6504942 | C/T | 6.71E-5 | 486 | 12.43 | 16.15 | 16.47 | KM Plot |
| THCA | rs45504694 | chr6:122720778 | C/A | 3.05E-7 | 478 | 15.93 | 15.27 | 22.5 | KM Plot |
| THCA | rs4555886 | chr6:79487382 | T/A | 1.46E-6 | 489 | 18.8 | 17.7 | 15.65 | KM Plot |
| THCA | rs45574139 | chr6:24419086 | C/T | 5.33E-15 | 489 | 16.33 | 14.85 | 11.07 | KM Plot |
| THCA | rs45590133 | chr6:24418854 | T/C | 5.33E-15 | 489 | 16.33 | 14.85 | 11.07 | KM Plot |
| THCA | rs45610932 | chr14:59787325 | G/C | 1.6E-8 | 486 | 16.37 | 12.7 | 5.45 | KM Plot |
| THCA | rs4589617 | chr17:16939619 | A/T | 0.00015 | 481 | 16.37 | 15.97 | 13.18 | KM Plot |
| THCA | rs4591174 | chr17:37658505 | G/A | 0.000268 | 486 | 15.83 | 16.17 | 15.63 | KM Plot |
| THCA | rs4593973 | chr11:93877376 | A/G | 9.04E-5 | 477 | 15.23 | 17.17 | 10.5 | KM Plot |
| THCA | rs4593997 | chr11:4168319 | A/G | 5.66E-6 | 485 | 18.33 | 15.23 | 16.22 | KM Plot |